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PPAPDC2 antibody

Anti-PPAPDC2 antibody used in Western Blot (WB). GTX85222
Anti-PPAPDC2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85222

Cat. No. GTX85222

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all PPAPDC2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
ICC/IF 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

Positive Control

Raji Cell Slide(GTX25538) , Raji Cell Lysate(GTX27908)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PPAPDC2 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus human PPAPDC2.The immunogen is located within amino acids 170 - 220 of PPAPDC2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phospholipid phosphatase 6 , PDP1 , PPAPDC2 , PSDP , bA6J24.6

Cellular Localization

Membrane

Background

PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.

Database

DATA IMAGES

Anti-PPAPDC2 antibody used in Western Blot (WB). GTX85222

GTX85222 WB Image

WB analysis of Raji cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX85222 PPAPDC2 antibody.
Working concentration : 1 μg/ml

Anti-PPAPDC2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85222

GTX85222 ICC/IF Image

ICC/IF analysis of Raji cells using GTX85222 PPAPDC2 antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399