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PRODH antibody

Anti-PRODH antibody used in Western Blot (WB). GTX33428
Anti-PRODH antibody used in IHC (Paraffin sections) (IHC-P). GTX33428

Cat. No. GTX33428

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all PRODH products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human PRODH (NP_057419.4).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887713

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

proline dehydrogenase 1 , HSPOX2 , PIG6 , POX , PRODH1 , PRODH2 , TP53I6

Cellular Localization

Mitochondrion matrix

Background

This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

Database

Research Area

DATA IMAGES

Anti-PRODH antibody used in Western Blot (WB). GTX33428

GTX33428 WB Image

WB analysis of various sample lysates using GTX33428 PRODH antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-PRODH antibody used in IHC (Paraffin sections) (IHC-P). GTX33428

GTX33428 IHC-P Image

IHC-P analysis of human liver damage tissue using GTX33428 PRODH antibody.
Dilution : 1:100

REFERENCE

Application Reference

Wang J et al. Biochem Pharmacol 2020; 178 : 114065 Proline improves cardiac remodeling following myocardial infarction and attenuates cardiomyocyte apoptosis via redox regulation.
Application : WB
Reactivity : Rat
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399