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PRX II antibody

KO/KD
Anti-PRX II antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54610
Anti-PRX II antibody used in Western Blot (WB). GTX54610
Anti-PRX II antibody used in Western Blot (WB). GTX54610

Cat. No. GTX54610

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all PRX II products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human PRDX2 (NP_859428.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

peroxiredoxin 2 , HEL-S-2a , NKEF-B , NKEFB , PRP , PRX2 , PRXII , PTX1 , TDPX1 , TPX1 , TSA

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]

Database

Research Area

DATA IMAGES

Anti-PRX II antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54610

GTX54610 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX54610 PRX II antibody.

Anti-PRX II antibody used in Western Blot (WB). GTX54610

GTX54610 WB Image

KO/KD

WB analysis of normal (control) and knockout (KO) 293T cell lysate using GTX54610 PRX II antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-PRX II antibody used in Western Blot (WB). GTX54610

GTX54610 WB Image

WB analysis of various sample lysates using GTX54610 PRX II antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399