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PSMA7 antibody [2A7]

Overexpression
Anti-PSMA7 antibody [2A7] used in Western Blot (WB). GTX83786
Anti-PSMA7 antibody [2A7] used in Western Blot (WB). GTX83786

Cat. No. GTX83786

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2A7

Isotype

 IgG1

Application

 WB

Reactivity

 Human
Package
100 μl ($519)
See all PSMA7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full-length protein expressed in 293T cell transfected with human PSMA7 expression vector

Purification

Purified by affinity chromatography
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

proteasome subunit alpha 7 , C6 , HEL-S-276 , HSPC , RC6-1 , XAPC7

Cellular Localization

Cytoplasm,Nucleus

Background

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.

Database

Research Area

DATA IMAGES

Anti-PSMA7 antibody [2A7] used in Western Blot (WB). GTX83786

GTX83786 WB Image

Overexpression

WB analysis of HEK293T cells transfected with PSMA7 plasmid (Right) or empty vector (Left) for 48 hrs using GTX83786 PSMA7 antibody [2A7].
Loading : 5 ug per lane

Anti-PSMA7 antibody [2A7] used in Western Blot (WB). GTX83786

GTX83786 WB Image

WB analysis of various cell lines using GTX83786 PSMA7 antibody [2A7].
Loading : 35 ug per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519