APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500-1:1000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide, corresponding to amino acids 51-100 of Human PGE synthase.
Purification
Purified by antigen-affinity chromatography
From serum
Purity
> 95% (by SDS-PAGE)
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
prostaglandin E synthase , MGST-IV , MGST1-L1 , MGST1L1 , MPGES , PGES , PIG12 , PP102 , PP1294 , TP53I12 , mPGES-1
Cellular Localization
Membrane
Background
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX66701 WB Image
WB analysis of various samples using GTX66701 PTGES antibody. Lane1 : NIH-3T3 whole cell lysate(40ug) Lane2 : Hela whole cell lysate(40ug) Lane3 : H9C2 whole cell lysate(40ug) Lane4 : SP2/0 whole cell lysate(40ug) Dilution : 1:500
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REFERENCE
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REVIEW
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