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Parkin antibody

Anti-Parkin antibody used in Western Blot (WB). GTX65812
Anti-Parkin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX65812

Cat. No. GTX65812

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Rat
Package
100 μl ($399)
See all Parkin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1-300 of human PARK2 (AAH22014.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

parkin RBR E3 ubiquitin protein ligase , AR-JP , LPRS2 , PARK2 , PDJ

Cellular Localization

Cytoplasm, cytosol,Nucleus,Endoplasmic reticulum,Mitochondrion

Background

The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Parkin antibody used in Western Blot (WB). GTX65812

GTX65812 WB Image

WB analysis of various sample lysates using GTX65812 Parkin antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Parkin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX65812

GTX65812 ICC/IF Image

ICC/IF analysis of A549 cells using GTX65812 Parkin antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399