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Progesterone Receptor antibody [4D8]

Cat. No. GTX70226

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4D8

Isotype

 IgG2a

Application

 WB

Reactivity

 Human
Package
100 μl ($399)
See all Progesterone Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 5 μg/ml
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Positive Control

MCF7 lysate (GTX23871) & recombinant protein

Product Note

This antibody recognizes both Form A (94 kDa) and Form B (120kDa) of the human progesterone receptor (PgR)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No Preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

6-His fusion protein containing the region encoding amino acids 1-101 of the human progesterone receptor expressed in E. coli.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

RRID

AB_372807

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

progesterone receptor , NR3C3 , PR

Cellular Localization

Nucleus , Cytoplasm

Background

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
Custom Conjugations