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Properdin antibody

Anti-Properdin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53957
Anti-Properdin antibody used in Western Blot (WB). GTX53957
Anti-Properdin antibody used in Western Blot (WB). GTX53957
Anti-Properdin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53957

Cat. No. GTX53957

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Properdin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 190-469 of human CFP (NP_001138724.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

complement factor properdin , BFD , PFC , PFD , PROPERDIN

Cellular Localization

Secreted

Background

This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]

Database

Research Area

DATA IMAGES

Anti-Properdin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53957

GTX53957 ICC/IF Image

ICC/IF analysis of NIH/3T3 cells using GTX53957 Properdin antibody.
Blue : DAPI
Dilution : 1:100

Anti-Properdin antibody used in Western Blot (WB). GTX53957

GTX53957 WB Image

WB analysis of Jurkat cell lysate using GTX53957 Properdin antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Properdin antibody used in Western Blot (WB). GTX53957

GTX53957 WB Image

WB analysis of mouse spleen tissue lysate using GTX53957 Properdin antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Properdin antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53957

GTX53957 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX53957 Properdin antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399