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RGNEF antibody

Anti-RGNEF antibody used in IHC (Paraffin sections) (IHC-P). GTX54661

Cat. No. GTX54661

Reference 1

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-P, IP

Reactivity

 Human
Package
50 μg ($399)
See all RGNEF products

APPLICATION

Application Note

IF: 1:100. IHC: 1:100 - 1:500. IP: 1 ug/ml

Calculated MW

192 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The human Rho-Guanine Nucleotide Exchange Factor (RGNEF) isoforms A and B.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Rho guanine nucleotide exchange factor 28 , RGNEF , RIP2 , p190RHOGEF

Cellular Localization

Cytoplasm , Cell membrane

Background

This gene encodes a member of the Rho guanine nucleotide exchange factor family. The encoded protein interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]

Database

Research Area

DATA IMAGES

Anti-RGNEF antibody used in IHC (Paraffin sections) (IHC-P). GTX54661

GTX54661 IHC-P Image

IHC-P analysis of motor neurons from (left) neuropathologically normal human spinal cord and (right) ALS affected spinal cord using RGNEF antibody at a dilution of 1 :500.

REFERENCE

Application Reference

Chih-I Chen et al. Life (Basel) 2021; 12 (1) Utility of RGNEF in the Prediction of Clinical Prognosis in Patients with Rectal Cancer Receiving Preoperative Concurrent Chemoradiotherapy.
Reactivity : Human
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REVIEW

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Package List Price ($)
$ 399