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ROR1 antibody [2H6]

Anti-ROR1 antibody [2H6] used in Western Blot (WB). GTX83359
Anti-ROR1 antibody [2H6] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83359

Cat. No. GTX83359

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2H6

Isotype

 IgG1

Application

 WB, ICC/IF, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all ROR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ICC/IF 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

104 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

receptor tyrosine kinase like orphan receptor 1 , NTRKR1 , dJ537F10.1

Cellular Localization

Membrane

Background

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]

Database

Research Area

DATA IMAGES

Anti-ROR1 antibody [2H6] used in Western Blot (WB). GTX83359

GTX83359 WB Image

WB analysis of extracellular domain of human ROR1 (aa30-423) using GTX83359 ROR1 antibody [2H6].

Anti-ROR1 antibody [2H6] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83359

GTX83359 ICC/IF Image

ICC/IF analysis of HEK293 cells trasfected with extracellular ROR1 (aa30-406)-hIgGFc using GTX83359 ROR1 antibody [2H6].
Green : ROR1
Blue: DRAQ5 fluorescent DNA dye

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399