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RRM1 antibody

Anti-RRM1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54666
Anti-RRM1 antibody used in Western Blot (WB). GTX54666
Anti-RRM1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54666

Cat. No. GTX54666

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all RRM1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

90 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 593-792 of human RRM1 (NP_001024.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ribonucleotide reductase catalytic subunit M1 , R1 , RIR1 , RR1

Cellular Localization

Cytoplasm

Background

This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Database

Research Area

DATA IMAGES

Anti-RRM1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54666

GTX54666 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX54666 RRM1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-RRM1 antibody used in Western Blot (WB). GTX54666

GTX54666 WB Image

WB analysis of various sample lysates using GTX54666 RRM1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-RRM1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54666

GTX54666 IHC-P Image

IHC-P analysis of human colon tissue using GTX54666 RRM1 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399