Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
RSRC1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human RSRC1.The immunogen is located within the last 50 amino acids of RSRC1.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
arginine and serine rich coiled-coil 1 , BM-011 , SFRS21 , SRrp53
Cellular Localization
Nucleus,Nucleus speckle,Cytoplasm
Background
The arginine/serine-rich coiled-coil 1 protein (RSRC1) was initially identified as a non-snRNP splicing factor that has a role in both the constitutive and alternative splicing of pre-mRNA molecules. In cellular nuclear extracts immunodepleted of RSRC1, the second step of pre-mRNA splicing is blocked; recombinant RSRC1 is able to restore splicing activity. RSRC1 has also been reported to be associated with schizophrenia as well as a unique marker of bone marrow-derived stem cells that also express the cdc34 marker.
Database
Research Area