Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Immunogen Sequence: GI # 14591926, sequence 219-530 Recombinant sec23 (S. cerevisiae) homolog B
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
Sec23 homolog B, coat complex II component , CDA-II , CDAII , CDAN2 , CWS7 , HEMPAS , hSec23B
Cellular Localization
Endoplasmic reticulum membrane,Cytoplasm, cytosol
Background
Component of the COPII coat. that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory. plasma membrane. and vacuolar proteins from the endoplasmic reticulum to the Golgi complex (By similarity). The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Database
Research Area