SFRP1 antibody

Cat. No. GTX03397

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, FACS
Reactivity	Human
Package	400 μl ($399)

See all SFRP1 products

Datasheet

View product citations for antibody GTX03397 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:1000
IHC-P	1:10-1:50
FACS	1:10-1:50

Not tested in other applications.

Calculated MW

35 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This SFRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human SFRP1.

Purification

Protein A purified followed by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

secreted frizzled related protein 1 , FRP , FRP-1 , FRP1 , FrzA , SARP2

Cellular Localization

Secreted

Background

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]

Database

Gene ID: 6422 SFRP1
UniProt: Q8N474 SFRP1

Research Area

DATA IMAGES

GTX03397 IHC-P Image

IHC-P analysis of human testis tissue using GTX03397 SFRP1 antibody.

GTX03397 WB Image

WB analysis of K562 cell lysates (35μg/lane) using GTX03397 SFRP1 antibody.

GTX03397 FACS Image

FACS analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram) using GTX03397 SFRP1 antibody.

REFERENCE

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REVIEW

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Package

List Price ($)

400 μl

$ 399

Qty