SH3BP4 antibody

Cat. No. GTX85017

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P, ELISA
Reactivity	Human, Mouse, Rat
Package	100 μg ($399)

See all SH3BP4 products

Datasheet
Document

View product citations for antibody GTX85017 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1 - 2 μg/mL
IHC-P	5 μg/mL
ELISA	Assay dependent

Not tested in other applications.

Calculated MW

107 kDa. ( Note )

Positive Control

Rat Lung Tissue Lysate(GTX27941) , Human Lung Tissue Slide

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SH3BP4 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human SH3BP4.The immunogen is located within amino acids 860 - 910 of SH3BP4.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SH3 domain binding protein 4 , BOG25 , TTP

Cellular Localization

Nucleus

Background

SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.

Database

Gene ID: 23677 SH3BP4
UniProt: Q9P0V3 SH3BP4

Research Area

DATA IMAGES

GTX85017 IHC-P Image

IHC-P analysis of human lung tissue using GTX85017 SH3BP4 antibody.
Working concentration : 5 μg/ml

GTX85017 WB Image

WB analysis of rat lung tissue lysate using GTX85017 SH3BP4 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

REFERENCE

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SDS
PBS.pdf
Sodium Azide.pdf

Package

List Price ($)

100 μg

$ 399

Qty