GeneTex

  • Country / Location Selection

United States (US)

SIGIRR antibody

Anti-SIGIRR antibody used in Western Blot (WB). GTX13717

Cat. No. GTX13717

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
200 μl ($399)
See all SIGIRR products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Serum diluted with PBS, 0.1mg/ml BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

This antibody was developed against synthetic peptides corresponding to aa 300-350 and 370-420 of human SIGIRR.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

single Ig and TIR domain containing , IL-1R8 , TIR8

Cellular Localization

Membrane

Background

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

Database

Research Area

DATA IMAGES

Anti-SIGIRR antibody used in Western Blot (WB). GTX13717

GTX13717 WB Image

WB analysis of (A) HCT-116 and (B) A549 cell lysate using GTX13717 SIGIRR antibody.
Loading : 40μg

REFERENCE

There are currently no references for SIGIRR antibody (GTX13717). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for SIGIRR antibody (GTX13717). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399