APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:100 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein of human SIGMAR1
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
sigma non-opioid intracellular receptor 1 , ALS16 , DSMA2 , OPRS1 , SIG-1R , SR-BP , SR-BP1 , SRBP , hSigmaR1 , sigma1R
Cellular Localization
Nucleus inner membrane,Nucleus outer membrane,Cytoplasmic vesicle,Endoplasmic reticulum membrane,Membrane,Cell junction,Cell membrane
Background
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013]
Database
Research Area
DATA IMAGES
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GTX33496 IHC-P Image
IHC-P analysis of mouse kidney tissue using GTX33496 SIGMAR1 antibody.
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GTX33496 IHC-P Image
IHC-P analysis of human stomach tissue using GTX33496 SIGMAR1 antibody.
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GTX33496 WB Image
WB analysis of various sample lysates using GTX33496 SIGMAR1 antibody.
Dilution : 1:500
Loading : 25μg per lane
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GTX33496 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX33496 SIGMAR1 antibody.
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REFERENCE
There are currently no references for SIGMAR1 antibody (GTX33496). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for SIGMAR1 antibody (GTX33496). Be the first to share your experience with this product.
