GeneTex

  • Country / Location Selection

United States (US)

SIPA1L3 antibody

Anti-SIPA1L3 antibody used in Western Blot (WB). GTX85226
Anti-SIPA1L3 antibody used in IHC (Paraffin sections) (IHC-P). GTX85226
Anti-SIPA1L3 antibody used in IHC (Paraffin sections) (IHC-P). GTX85226

Cat. No. GTX85226

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all SIPA1L3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

195 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , SK-N-SH Cell Lysate(GTX23956)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SIPA1L3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human SIPA1L3.The immunogen is located within amino acids 80 - 130 of SIPA1L3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

signal induced proliferation associated 1 like 3 , CTRCT45 , SPAL3 , SPAR3

Cellular Localization

Apical cell membrane

Background

Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice (3) and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.

Database

Research Area

DATA IMAGES

Anti-SIPA1L3 antibody used in Western Blot (WB). GTX85226

GTX85226 WB Image

WB analysis of SK-N-SH cell lysate using GTX85226 SIPA1L3 antibody.
Working concentration : 1 μg/ml

Anti-SIPA1L3 antibody used in IHC (Paraffin sections) (IHC-P). GTX85226

GTX85226 IHC-P Image

IHC-P analysis of human brain tissue using GTX85226 SIPA1L3 antibody.
Working concentration : 5 μg/ml

Anti-SIPA1L3 antibody used in IHC (Paraffin sections) (IHC-P). GTX85226

GTX85226 IHC-P Image

IHC-P analysis of human brain tissue using GTX85226 SIPA1L3 antibody.
Working concentration : 20 μg/ml

REFERENCE

There are currently no references for SIPA1L3 antibody (GTX85226). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for SIPA1L3 antibody (GTX85226). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399