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SIRT6 antibody

Anti-SIRT6 antibody used in Western Blot (WB). GTX01549
Anti-SIRT6 antibody used in IHC (Paraffin sections) (IHC-P). GTX01549
Anti-SIRT6 antibody used in IHC (Paraffin sections) (IHC-P). GTX01549

Cat. No. GTX01549

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μg ($429)
See all SIRT6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.5μg/ml
IHC-P 0.5-1μg/ml

Note :

IHC-P
Antigen retrieval by heat
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

5mg BSA, 0.9mg NaCl, 0.2mg Na₂HPO₄

Preservative

0.05mg Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

E.coli-derived human SIRT6 recombinant protein (Position: D14-E180).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

,SIR2L6,SIRT6,sirtuin 6

Cellular Localization

Nucleus,Nucleoplasm

Background

This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Database

Research Area

DATA IMAGES

Anti-SIRT6 antibody used in Western Blot (WB). GTX01549

GTX01549 WB Image

WB analysis of various samples using GTX01549 SIRT6 antibody.
Lane 1 : HeLa whole cell lysate at 40μg
Lane 2 : A549 whole cell lysate at 40μg
Lane 3 : human placenta tissue lysate at 50μg
Dilution : 0.5μg/ml

Anti-SIRT6 antibody used in IHC (Paraffin sections) (IHC-P). GTX01549

GTX01549 IHC-P Image

IHC-P analysis of human mammary cancer tissue using GTX01549 SIRT6 antibody.

Anti-SIRT6 antibody used in IHC (Paraffin sections) (IHC-P). GTX01549

GTX01549 IHC-P Image

IHC-P analysis of mouse cardiac muscle tissue using GTX01549 SIRT6 antibody.

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 429