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SLC22A1 antibody [2C5]

Anti-SLC22A1 antibody [2C5] used in Western Blot (WB). GTX80400
Anti-SLC22A1 antibody [2C5] used in Flow cytometry (FACS). GTX80400

Cat. No. GTX80400

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2C5

Isotype

 IgG1

Application

 WB, FACS, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all SLC22A1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human SLC22A1 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_11174694

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 22 member 1 , HOCT1 , OCT1 , oct1_cds

Background

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SLC22A1 antibody [2C5] used in Western Blot (WB). GTX80400

GTX80400 WB Image

WB analysis of HEK293 (1) and SLC22A1(AA: 284-347)-hIgGFc transfected HEK293 (2) cell lysate using GTX80400 SLC22A1 antibody [2C5].

Anti-SLC22A1 antibody [2C5] used in Flow cytometry (FACS). GTX80400

GTX80400 FACS Image

FACS analysis of Jurkat cells using GTX80400 SLC22A1 antibody [2C5].
Green : SLC22A1
Purple : negative control

REFERENCE

Application Reference

Hahn D et al. J Clin Pharmacol 2020; (Epub) Influence of MRP3 Genetics and Hepatic Expression Ontogeny for Morphine Disposition in Neonatal and Pediatric Patients.
Hahn D et al. Drug Metab Dispos 2017; 45 (1) : 23-26 Developmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to Children.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399