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SLC7A8 antibody [8B12]

Overexpression
Anti-SLC7A8 antibody [8B12] used in IHC (Paraffin sections) (IHC-P). GTX83620
Anti-SLC7A8 antibody [8B12] used in Western Blot (WB). GTX83620
Anti-SLC7A8 antibody [8B12] used in Western Blot (WB). GTX83620

Cat. No. GTX83620

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8B12

Isotype

 IgG1

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Monkey
Package
100 μl ($519)
See all SLC7A8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:200-1:1000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full-length protein expressed in 293T cell transfected with human SLC7A8 expression vector

Purification

Purified by affinity chromatography
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 7 member 8 , LAT2 , LPI-PC1

Cellular Localization

Cytoplasm

Background

Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.

Database

Research Area

DATA IMAGES

Anti-SLC7A8 antibody [8B12] used in IHC (Paraffin sections) (IHC-P). GTX83620

GTX83620 IHC-P Image

IHC-P analysis of kidney carcinoma tissue using GTX83620 SLC7A8 antibody [8B12].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.
Dilution : 1:50

Anti-SLC7A8 antibody [8B12] used in Western Blot (WB). GTX83620

GTX83620 WB Image

WB analysis of various cell lines using GTX83620 SLC7A8 antibody [8B12].
Loading : 10 ug per lane
Dilution : 1:200

Anti-SLC7A8 antibody [8B12] used in Western Blot (WB). GTX83620

GTX83620 WB Image

Overexpression

WB analysis of HEK293T cells transfected with SLC7A8 plasmid (Right) or empty vector (Left) for 48 hrs using GTX83620 SLC7A8 antibody [8B12].
Loading : 5 ug per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519