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SLITRK6 antibody

Anti-SLITRK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85411
Anti-SLITRK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85411
Anti-SLITRK6 antibody used in Western Blot (WB). GTX85411

Cat. No. GTX85411

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all SLITRK6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

95 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Mouse Lung Tissue Lysate(GTX27933)

Product Note

This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Slitrk6 antibody was raised against a 13 amino acid synthetic peptide from near the center of human Slitrk6.The immunogen is located within amino acids 250 - 300 of Slitrk6.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SLIT and NTRK like family member 6 , DFNMYP

Cellular Localization

Cell membrane

Background

SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family (1,2). Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of Slitrk6 are known to exisit. This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Database

Research Area

DATA IMAGES

Anti-SLITRK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85411

GTX85411 IHC-P Image

IHC-P analysis of human brain tissue using GTX85411 SLITRK6 antibody.
Working concentration : 20 μg/ml

Anti-SLITRK6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85411

GTX85411 IHC-P Image

IHC-P analysis of human brain tissue using GTX85411 SLITRK6 antibody.
Working concentration : 2.5 μg/ml

Anti-SLITRK6 antibody used in Western Blot (WB). GTX85411

GTX85411 WB Image

WB analysis of mouse lung tissue lysate using GTX85411 SLITRK6 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

REFERENCE

Application Reference

Kim EJ et al. Nucleic Acids Res 2021; 49 (21) : 12211-12233 BAF155 methylation drives metastasis by hijacking super-enhancers and subverting anti-tumor immunity.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399