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SPG11 antibody

Anti-SPG11 antibody used in IHC (Paraffin sections) (IHC-P). GTX31970
Anti-SPG11 antibody used in Western Blot (WB). GTX31970

Cat. No. GTX31970

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all SPG11 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

279 kDa. ( Note )

Positive Control

Mouse Heart Tissue Lysate(GTX27932)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SPG11 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SPG11.The immunogen is located within amino acids 2360 - 2410 of SPG11.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SPG11 vesicle trafficking associated, spatacsin , ALS5 , CMT2X , KIAA1840

Cellular Localization

Cytoplasm, cytosol,Nucleus,Cell projection, dendrite

Background

The protein encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Database

Research Area

DATA IMAGES

Anti-SPG11 antibody used in IHC (Paraffin sections) (IHC-P). GTX31970

GTX31970 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31970 SPG11 antibody.
Working concentration : 2.5 μg/ml

Anti-SPG11 antibody used in Western Blot (WB). GTX31970

GTX31970 WB Image

WB analysis of mouse heart tissue lysate using GTX31970 SPG11 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399