APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 - 2 μg/mL |
2.5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Prostate Tissue Lysate(GTX29184)
Product Note
This STEAP2 antibody does not cross-react with other STEAP proteins.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
STEAP2 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human STEAP2.The immunogen is located within the last 50 amino acids of STEAP2.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
STEAP2 metalloreductase , IPCA1 , PCANAP1 , PUMPCn , STAMP1 , STMP
Cellular Localization
Endosome membrane,Cell membrane
Background
The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist. This STEAP2 antibody does not cross-react with other STEAP proteins.
Database
DATA IMAGES
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GTX85435 IHC-P Image
IHC-P analysis of human colon tissue using GTX85435 STEAP2 antibody. Working concentration : 20 μg/ml
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GTX85435 IHC-P Image
IHC-P analysis of human colon tissue using GTX85435 STEAP2 antibody. Working concentration : 2.5 μg/ml
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GTX85435 WB Image
WB analysis of human prostate tissue lysate using GTX85435 STEAP2 antibody. Working concentration : 1 μg/ml
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REFERENCE
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REVIEW
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