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StAR antibody [STAR/2140]

Anti-StAR antibody [STAR/2140] used in IHC (Paraffin sections) (IHC-P). GTX18017
Anti-StAR antibody [STAR/2140] used in IHC (Paraffin sections) (IHC-P). GTX18017
Anti-StAR antibody [STAR/2140] used in Protein Array (Protein Array). GTX18017

Cat. No. GTX18017

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 STAR/2140

Isotype

 IgG2b

Application

 IHC-P, Protein Array

Reactivity

 Human
Package
100 μg ($529)
See all StAR products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml for 30 min at RT
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (around aa 39-108) of human STAR protein (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

STAR , STARD1 , steroidogenic acute regulatory protein , StAR

Cellular Localization

Mitochondrion

Background

The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-StAR antibody [STAR/2140] used in IHC (Paraffin sections) (IHC-P). GTX18017

GTX18017 IHC-P Image

IHC-P analysis of human testicular carcinoma tissue using GTX18017 StAR antibody [STAR/2140].

Anti-StAR antibody [STAR/2140] used in IHC (Paraffin sections) (IHC-P). GTX18017

GTX18017 IHC-P Image

IHC-P analysis of human adrenal gland tissue using GTX18017 StAR antibody [STAR/2140].

Anti-StAR antibody [STAR/2140] used in Protein Array (Protein Array). GTX18017

GTX18017 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using StAR Mouse Monoclonal Antibody (STAR/2140). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529