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Stanniocalcin 2 antibody

Cat. No. GTX82231

Reference 3

Host

 Chicken

Clonality

 Polyclonal

Isotype

 IgY

Application

 WB

Reactivity

 Human, Goat
Package
50 μg ($519)
See all Stanniocalcin 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Immunogen Sequence: GI # 4507267, sequence 20-302 Recombinant stanniocalcin 2

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_1081450

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

stanniocalcin 2 , STC-2 , STCRP

Cellular Localization

Secreted

Background

Has an anti-hypocalcemic action on calcium and phosphate homeostasis. This protein is a secreted. homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport. cell metabolism. or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction. reduced bone and skeletal muscle growth. and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Database

Research Area

REFERENCE

Application Reference

Chao Zhu et al. BMC Genomics 2021; 22 (1) : 703 Exploration of the lactation function of protein phosphorylation sites in goat mammary tissues by phosphoproteome analysis.
Application : WB
Reactivity : Goat
Cui J et al. Genes (Basel) 2020; 11 (9) MiR-184 Combined with STC2 Promotes Endometrial Epithelial Cell Apoptosis in Dairy Goats via RAS/RAF/MEK/ERK Pathway.
Application : WB
Zhu C et al. Animals (Basel) 2020; 10 (8) CircRNA8220 Sponges MiR-8516 to Regulate Cell Viability and Milk Synthesis via Ras/MEK/ERK and PI3K/AKT/mTOR Pathways in Goat Mammary Epithelial Cells.
Application : WB
Reactivity : Goat
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519