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Staphylococcal Enterotoxin B antibody [SEB]

Cat. No. GTX20686

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SEB

Isotype

 IgG

Application

 ELISA
Package
100 μg ($399)
See all Staphylococcal Enterotoxin B products

APPLICATION

Application Note

Staphylococcal enterotoxin B (SEB), as a superantigen for T-lymphocytes, is a potential targeting antigen in cancer immunotherapy.

Product Note

Antibodies were screened for SEB binding by ELISA using SEB coated plates

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Full length native protein (purified).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

EntB Enterotoxin type B SEB

Cellular Localization

Secreted

Background

Staphylococcal enterotoxins represent a group of proteins, which are secreted by Staphylococcus aureus and cause the intoxication staphylococcal food poisoning syndrome. The illness is characterised by high fever, hypotension, diarrhea, shock, and in some cases death. Their molecular masses range between 27 and 30 kDa. At present, seven enterotoxins are known, namely A, B, C1, C2, C3, D and E. Their amino acid sequences have been determined and it was shown that all are single chain polypeptides containing one disulfide bond formed by two half cystines located in the middle of the polypeptide chain, which form the so called cysteine loop. Enterotoxins are known to be most potent T cell mitogens. T cell activation accompanied by induction of interleukin 2 and interferon is conditioned by high affinity interaction of S.enterotoxins with class II main histocompatibility complex (MHC) molecules and subsequent presentation of the complex formed to a variable region of the T cell receptor.

Research Area

REFERENCE

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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations