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TCF3 / E2A antibody [6B8]

Anti-TCF3 / E2A antibody [6B8] used in Flow cytometry (FACS). GTX83355
Anti-TCF3 / E2A antibody [6B8] used in Western Blot (WB). GTX83355

Cat. No. GTX83355

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6B8

Isotype

 IgG1

Application

 WB, FACS, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all TCF3 / E2A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human TCF3 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transcription factor 3 , AGM8 , E2A , E47 , ITF1 , TCF-3 , VDIR , bHLHb21 , p75

Cellular Localization

Nucleus

Background

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of c

Database

Research Area

DATA IMAGES

Anti-TCF3 / E2A antibody [6B8] used in Flow cytometry (FACS). GTX83355

GTX83355 FACS Image

FACS analysis of A549 cells using GTX83355 TCF3 / E2A antibody [6B8].
Green : TCF3
Purple : negative control

Anti-TCF3 / E2A antibody [6B8] used in Western Blot (WB). GTX83355

GTX83355 WB Image

WB analysis of A549 (1), A431 (2), HeLa (3), PANC-1 (4) and PC-3 (5) cell lysate using GTX83355 TCF3 / E2A antibody [6B8].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399