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TCPTP antibody

Anti-TCPTP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54634
Anti-TCPTP antibody used in IHC (Paraffin sections) (IHC-P). GTX54634
Anti-TCPTP antibody used in Western Blot (WB). GTX54634

Cat. No. GTX54634

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all TCPTP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human PTPN2 (NP_536348.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

protein tyrosine phosphatase non-receptor type 2 , PTN2 , PTPT , TC-PTP , TCELLPTP , TCPTP

Cellular Localization

Cytoplasm,Cell membrane

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]

Database

Research Area

DATA IMAGES

Anti-TCPTP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54634

GTX54634 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX54634 TCPTP antibody.
Blue : DAPI

Anti-TCPTP antibody used in IHC (Paraffin sections) (IHC-P). GTX54634

GTX54634 IHC-P Image

IHC-P analysis of rat heart tissue using GTX54634 TCPTP antibody.
Dilution : 1:100

Anti-TCPTP antibody used in Western Blot (WB). GTX54634

GTX54634 WB Image

WB analysis of various sample lysates using GTX54634 TCPTP antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399