APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:1000 |
| 1:50 - 1:200 |
| 1:50 - 1:100 |
| 1:50 - 1:100 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Ascites
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Full-length recombinant human Telomerase reverse transcriptase from insect cells. [UniProt# O14746]
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
telomerase reverse transcriptase , CMM9 , DKCA2 , DKCB4 , EST2 , PFBMFT1 , TCS1 , TP2 , TRT , hEST2 , hTRT
Cellular Localization
nucleoplasm,Nucleus,Cytoplasm,Nucleolus
Background
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq]
Database
Research Area
DATA IMAGES
![Anti-TERT antibody [2D8] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25405](/templates/default/js/lightbox/images/loading.gif "Anti-TERT antibody [2D8] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25405")
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GTX25405 ICC/IF Image
ICC/IF analysis of HepG2 cells using GTX25405 TERT antibody [2D8].
Green : primary antibody
Blue : Hoechst 33258
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GTX25405 WB Image
WB analysis of MJ90 cell lysate using GTX25405 TERT antibody [2D8].
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GTX25405 IHC-P Image
IHC-P analysis of human liver cancer tissue using GTX25405 TERT antibody [2D8].
Dilution : 1:600
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REFERENCE
There are currently no references for TERT antibody [2D8] (GTX25405). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TERT antibody [2D8] (GTX25405). Be the first to share your experience with this product.
![Anti-TERT antibody [2D8] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25405](/upload/website/prouct_img/small/GTX25405/GTX25405_162_ICC-IF_w_23060722_274.webp "Anti-TERT antibody [2D8] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25405")
![Anti-TERT antibody [2D8] used in Western Blot (WB). GTX25405](/upload/website/prouct_img/small/GTX25405/GTX25405_1297_WB_w_23060722_870.webp "Anti-TERT antibody [2D8] used in Western Blot (WB). GTX25405")
![Anti-TERT antibody [2D8] used in IHC (Paraffin sections) (IHC-P). GTX25405](/upload/website/prouct_img/small/GTX25405/GTX25405_524_IHC-P_w_23060722_854.webp "Anti-TERT antibody [2D8] used in IHC (Paraffin sections) (IHC-P). GTX25405")
![Anti-TERT antibody [2D8] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25405](/upload/website/prouct_img/normal/GTX25405/GTX25405_162_ICC-IF_w_23060722_274.webp "Anti-TERT antibody [2D8] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX25405")
![Anti-TERT antibody [2D8] used in Western Blot (WB). GTX25405](/upload/website/prouct_img/normal/GTX25405/GTX25405_1297_WB_w_23060722_870.webp "Anti-TERT antibody [2D8] used in Western Blot (WB). GTX25405")
![Anti-TERT antibody [2D8] used in IHC (Paraffin sections) (IHC-P). GTX25405](/upload/website/prouct_img/normal/GTX25405/GTX25405_524_IHC-P_w_23060722_854.webp "Anti-TERT antibody [2D8] used in IHC (Paraffin sections) (IHC-P). GTX25405")