GeneTex
United States (US)

TGF-alpha recombinant protein

Cat No. GTX65264

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The ED50 as determined by the dose-dependent stimulation of proliferation of Balb-c 3T3 cells is <0.2 ng/ml, corresponding to a specific activity of >5x10^6 units/mg.

Calculated MW

5.5 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4ºC for 1 week or –20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

TGF-type I, Transforming Growth Factor-alpha, Transforming Growth Factoralpha, ETGF, TGFA, Sacroma growth factor, TGFtype I, TGF type I

Background

Transforming Growth Factor-alpha (TGF-alpha ) stimulates the proliferation of a wide range of epidermal and epithelial cells. TGF-alpha has been shown to play a role in the autocrine growth of certain transformed cells. Human TGF-alpha is a 5.5 kDa protein containing 50 amino acid residues.

Research Area