GeneTex
United States (US)

TGF beta 2 recombinant protein

Cat No. GTX65265

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The ED50 as determined by the ability of TGF-beta2 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is <0.2 ng/ml, corresponding to a specific activity of > 5x10^6 units/mg.

Calculated MW

25.0 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute in 1 mM Citrate buffer (pH 3.5) to a concentration of 100-1000 ug/ml. The solution can then be stored at 4ºC for 1 month. It is recommended that further dilutions be made into PBS containing 2 mg/ml albumin and stored at –20ºC.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Polyergin, Glioblastoma-derived T cell suppressor factor, BSC-1, TGFB2, BSC1, Transforming Growth Factorbeta2, Glioblastomaderived T cell suppressor factor, Cetermin, Transforming Growth Factor-beta2, BSC 1

Background

TGF-beta2 (Transforming Growth Factor-beta2) is a member of the superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-beta2 is a 25 kDa protein with each subunit containing 112 amino acid residues.

Research Area