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TGF beta Receptor I antibody

Anti-TGF beta Receptor I antibody used in Western Blot (WB). GTX57156
Anti-TGF beta Receptor I antibody used in Western Blot (WB). GTX57156

Cat. No. GTX57156

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μl ($419)
See all TGF beta Receptor I products

APPLICATION

Application Note

WB: 1:500 - 1:1000, ICC/IF: 1:50 - 1:200

Calculated MW

56 kDa. ( Note )

Product Note

TGFβ RI (E161) pAb detects endogenous levels of TGFβ RI protein.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 150-200 of Human TGFβ RI.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

RRID

AB_2887951

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transforming growth factor beta receptor 1 , AAT5 , ACVRLK4 , ALK-5 , ALK5 , ESS1 , LDS1 , LDS1A , LDS2A , MSSE , SKR4 , TBR-i , TBRI , TGFR-1 , tbetaR-I

Cellular Localization

Cell membrane

Background

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Database

Research Area

DATA IMAGES

Anti-TGF beta Receptor I antibody used in Western Blot (WB). GTX57156

GTX57156 WB Image

Western blot (WB) analysis of TGFβ RI pAb at 1:500 dilution Lane1:Hela cell lysate Lane2:LO2 cell lysate Lane3:Raw264.7 cell lysate Lane4:Mouse kidney tissue lysate Lane5:Rat heat tissue lysate

Anti-TGF beta Receptor I antibody used in Western Blot (WB). GTX57156

GTX57156 WB Image

Western blot (WB) analysis of TGFβ RI pAb at 1:1000 dilution Lane1:The Liver tissue lysate of Rat(40ug) Lane2:The Liver tissue lysate of mouse(40ug) Lane3:L02 whole cell lysate(40ug) Lane4:The Heart tissue lysate of Rat(40ug)

REFERENCE

Application Reference

Hsu HY et al. Oncotarget 2014; 5 (17) : 7870-85 Fucoidan inhibition of lung cancer in vivo and in vitro : role of the Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradation.
Application : WB
Reactivity : Human
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419