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TGF beta Receptor III antibody [5G9]

Anti-TGF beta Receptor III antibody [5G9] used in IHC (Paraffin sections) (IHC-P). GTX52508

Cat. No. GTX52508

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5G9

Isotype

 IgG1

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all TGF beta Receptor III products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:100 - 1:1000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

Product Note

No cross reactivity was found to TGF beta receptor 1 and receptor 3.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant huTGFβRIII extra cellular domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BGCAN , TGFBR3 , betaglycan , transforming growth factor beta receptor 3 , TGF beta Receptor III , TGF beta receptor 3

Cellular Localization

Secreted,Extracellular space,Cell membrane

Background

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]

Database

Research Area

DATA IMAGES

Anti-TGF beta Receptor III antibody [5G9] used in IHC (Paraffin sections) (IHC-P). GTX52508

GTX52508 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52508 TGF beta Receptor III antibody [5G9].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399