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TGF beta antibody [1D11.16.8]

Anti-TGF beta antibody [1D11.16.8] used in Western Blot (WB). GTX14052

Cat. No. GTX14052

Reference 8

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1D11.16.8

Isotype

 IgG1

Application

 WB, in vitro, in vivo, Neutralizing/Inhibition

Reactivity

 Human, Mouse, Rat, Bovine, Dog, Hamster, Monkey
Package
500 μg ($399)
See all TGF beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
in vitro Assay dependent
in vivo Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

Product Note

The 1D11.16.8 monoclonal antibody reacts with isoforms 1, 2 and 3.

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Bovine

Immunogen

Bovine TGFβ isoform 2

Purification

Protein G purified
From tissue culture supernatant

Purity

>95% (Determined by SDS-PAGE)

Endotoxin

< 0.002 EU/弮g (Determined by LAL assay)

Conjugation

Unconjugated

RRID

AB_2887508

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Secreted,Extracellular space,Extracellular matrix

Database

Research Area

DATA IMAGES

Anti-TGF beta antibody [1D11.16.8] used in Western Blot (WB). GTX14052

GTX14052 WB Image

WB analysis of purified TGF beta recombinant protein using GTX14052 TGF beta antibody [1D11.16.8].
Lane 1 : 2 ug reduced purified mouse TGF-B isoform 2 with histidine tag at C-terminus
Lane 2 : 1 ug reduced purified mouse TGF-B isoform 2 with histidine tag at C-terminus
Dilution : 8 ug/ml

REFERENCE

Application Reference

Kwon SM et al. iScience 2020; 23 (6) : 101247 Mitoribosome Defect in Hepatocellular Carcinoma Promotes an Aggressive Phenotype with Suppressed Immune Reaction.
Watanabe H et al. Sci Rep 2020; 10 (1) : 9211 The neovascularization effect of dedifferentiated fat cells.
Application : Neutralizing/Inhibition
Friedrich M et al. Mucosal Immunol 2019; (Epub) HDAC inhibitors promote intestinal epithelial regeneration via autocrine TGFβ1 signalling in inflammation.
Okrah K et al. NPJ Precis Oncol 2018; 2 : 25 Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology.
Application : Neutralizing/Inhibition
Reactivity : Human
Cai X et al. J Cell Mol Med 2018; (Epub) CXCL6-EGFR-induced Kupffer cells secrete TGF-β1 promoting hepatic stellate cell activation via the SMAD2/BRD4/C-MYC/EZH2 pathway in liver fibrosis.
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Package List Price ($)
$ 399