APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:2000 |
| 1:100-1:500 |
| 1:100-1:500 |
| 1:50 |
Not tested in other applications.
Predict Reactivity
Bovine, Dog, Guinea pig, Pig(>80% identity)
PROPERTIES
Form
Liquid
Buffer
10mM TBS, 1% BSA, 50% Glycerol
Preservative
0.03% Proclin300
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide derived from human TGF Beta 1 (301-350).
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
transforming growth factor beta 1 , transforming growth factor beta 2 , transforming growth factor beta 3 , CED , DPD1 , IBDIMDE , LAP , TGFB , TGFbeta , G-TSF , LDS4 , TGF-beta2 , ARVD , ARVD1 , LDS5 , RNHF , TGF-beta3
Cellular Localization
Extracellular matrix , Secreted
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]
Database
Research Area
DATA IMAGES
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GTX03464 WB Image
WB analysis of MDA-MB-231 whole cell lysate using GTX03464 TGF beta antibody.
Dilution : 1:300
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GTX03464 FACS Image
FACS analysis of 4% PFA-fixed K562 cells using GTX03464 TGF beta antibody. Acquisitions of 20,000 events were performed.
Green : Primary antibody
Orange : Isotype control
Permeabilization : 0.1% PBST for 20 min at room temperature
Dilution : 1:50
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GTX03464 IHC-P Image
IHC-P analysis of rat brain tissue using GTX03464 TGF beta antibody.
Dilution : 1:200
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GTX03464 WB Image
WB analysis of rabbit spleen tissue lysate using GTX03464 TGF beta antibody.
Dilution : 1:300
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GTX03464 WB Image
WB analysis of mouse stomach tissue lysate using GTX03464 TGF beta antibody.
Dilution : 1:300
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REFERENCE
There are currently no references for TGF beta antibody (GTX03464). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TGF beta antibody (GTX03464). Be the first to share your experience with this product.
