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TLR4 antibody

Anti-TLR4 antibody used in Western Blot (WB). GTX21436

Cat No. GTX21436

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, FACS
Reactivity Human
Package
50 μg ($289)
APPLICATION

Application Note

For WB: Use at a dilution of 1:2,700 - 1:3,300. The use of this product is also suitable for flow cytometry but not yet reported. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

96 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline, pH 7.2, containing 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment - amino acids 6-169 of human TLR4

Purification

Protein A affinity purified
From polyclonal serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Toll Like Receptor 4,Armd10,Cd284,Tlr-4,Toll,Tlr4

Background

TLR4 (Toll-like receptor 4) is a mammalian homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.

Database

Research Area

DATA IMAGES
Anti-TLR4 antibody used in Western Blot (WB). GTX21436

GTX21436 WB Image

Human TLR4 detected by Western blot in transfected HEK293 cells (left lane)

REFERENCE
There are currently no references for TLR4 antibody (GTX21436). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TLR4 antibody (GTX21436). Be the first to share your experience with this product.
Package List Price ($)
$ 289