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TMEM184C antibody

Anti-TMEM184C antibody used in IHC (Paraffin sections) (IHC-P). GTX85192
Anti-TMEM184C antibody used in Western Blot (WB). GTX85192
Anti-TMEM184C antibody used in IHC (Paraffin sections) (IHC-P). GTX85192

Cat. No. GTX85192

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all TMEM184C products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Positive Control

Mouse Heart Tissue Lysate(GTX27932)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TMEM184C antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TMEM184C.The immunogen is located within amino acids 340 - 390 of TMEM184C.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transmembrane protein 184C , TMEM34

Cellular Localization

Membrane

Background

Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.

Database

DATA IMAGES

Anti-TMEM184C antibody used in IHC (Paraffin sections) (IHC-P). GTX85192

GTX85192 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX85192 TMEM184C antibody.
Working concentration : 5 μg/ml

Anti-TMEM184C antibody used in Western Blot (WB). GTX85192

GTX85192 WB Image

WB analysis of mouse heart tissue lysate using GTX85192 TMEM184C antibody.
Working concentration : 1 μg/ml

Anti-TMEM184C antibody used in IHC (Paraffin sections) (IHC-P). GTX85192

GTX85192 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX85192 TMEM184C antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399