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TOP1MT antibody

Anti-TOP1MT antibody used in Western Blot (WB). GTX66397
Anti-TOP1MT antibody used in IHC (Paraffin sections) (IHC-P). GTX66397
Anti-TOP1MT antibody used in IHC (Paraffin sections) (IHC-P). GTX66397

Cat. No. GTX66397

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all TOP1MT products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:200 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

70 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 470-550 of human TOP1MT (NP_443195.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DNA topoisomerase I mitochondrial

Cellular Localization

Mitochondrion

Background

This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

Database

Research Area

DATA IMAGES

Anti-TOP1MT antibody used in Western Blot (WB). GTX66397

GTX66397 WB Image

WB analysis of A549 cell lysate using GTX66397 TOP1MT antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-TOP1MT antibody used in IHC (Paraffin sections) (IHC-P). GTX66397

GTX66397 IHC-P Image

IHC-P analysis of human colon tissue using GTX66397 TOP1MT antibody.
Dilution : 1:100

Anti-TOP1MT antibody used in IHC (Paraffin sections) (IHC-P). GTX66397

GTX66397 IHC-P Image

IHC-P analysis of rat lung tissue using GTX66397 TOP1MT antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399