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TORC2 antibody

Anti-TORC2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31879
Anti-TORC2 antibody used in Western Blot (WB). GTX31879
Anti-TORC2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31879
Anti-TORC2 antibody used in Western Blot (WB). GTX31879

Cat. No. GTX31879

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all TORC2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

73 kDa. ( Note )

Positive Control

Human Small Intestine Tissue Lysate(GTX27923) , Human Small Intestine Tissue Slide

Product Note

Multiple isoforms are known to exist.This antibody is predicted to not cross-react with CRTC1.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TORC2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TORC2 .The immunogen is located within the last 50 amino acids of TORC2 .

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887632

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CREB regulated transcription coactivator 2 , TORC-2 , TORC2

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]

Database

Research Area

DATA IMAGES

Anti-TORC2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31879

GTX31879 IHC-P Image

IHC-P analysis of human small intestine tissue using GTX31879 TORC2 antibody.
Working concentration : 20 μg/ml

Anti-TORC2 antibody used in Western Blot (WB). GTX31879

GTX31879 WB Image

WB analysis of human small intestine tissue lysate using GTX31879 TORC2 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-TORC2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31879

GTX31879 IHC-P Image

IHC-P analysis of human small intestine tissue using GTX31879 TORC2 antibody.
Working concentration : 2.5 μg/ml

Anti-TORC2 antibody used in Western Blot (WB). GTX31879

GTX31879 WB Image

The data was published in the journal Int J Mol Sci in 2019. PMID: 31540136

REFERENCE

Application Reference

Lee MY et al. Int J Mol Sci 2019; 20 (18) Liraglutide Inhibits Hepatitis C Virus Replication Through an AMP Activated Protein Kinase Dependent Mechanism.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399