APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.5 - 1 μg/mL |
2.5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Spleen Tissue Lysate(GTX27921) , Human Spleen Tissue Slide
Product Note
TREX1 antibody will not cross-react with the related protein TREX2. At least three isoforms of TREX1 are known to exist; this antibody will recognize all three isoforms.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
TREX1 antibody was raised against a 15 amino acid synthetic peptide near the center of human TREX1.The immunogen is located within amino acids 220 - 270 of TREX1.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
three prime repair exonuclease 1 , AGS1 , CRV , DRN3 , HERNS
Cellular Localization
Nucleus,Cytoplasm, cytosol
Background
This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
Database
Research Area
DATA IMAGES
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GTX31367 WB Image
WB analysis of human spleen tissue lysate using GTX31367 TREX1 antibody. Working concentration : (A) 0.5 and (B) 1 μg/ml
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GTX31367 IHC-P Image
IHC-P analysis of human spleen tissue using GTX31367 TREX1 antibody. Working concentration : 20 μg/ml
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GTX31367 IHC-P Image
IHC-P analysis of human spleen tissue using GTX31367 TREX1 antibody. Working concentration : 2.5 μg/ml
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REFERENCE
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REVIEW
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