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TRMT1 antibody

Anti-TRMT1 antibody used in Western Blot (WB). GTX65595
Anti-TRMT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX65595
Anti-TRMT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX65595

Cat. No. GTX65595

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all TRMT1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 460-659 of human TRMT1 (NP_060192.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tRNA methyltransferase 1 , MRT68 , TRM1

Background

This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome. [provided by RefSeq, May 2017]

Database

DATA IMAGES

Anti-TRMT1 antibody used in Western Blot (WB). GTX65595

GTX65595 WB Image

WB analysis of various sample lysates using GTX65595 TRMT1 antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-TRMT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX65595

GTX65595 IHC-P Image

IHC-P analysis of human stomach tissue using GTX65595 TRMT1 antibody.
Dilution : 1:100

Anti-TRMT1 antibody used in IHC (Paraffin sections) (IHC-P). GTX65595

GTX65595 IHC-P Image

IHC-P analysis of human lung cancer tissue using GTX65595 TRMT1 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399