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TSC2 (phospho Ser1254) antibody

Anti-TSC2 (phospho Ser1254) antibody used in IHC (Paraffin sections) (IHC-P). GTX78927

Cat. No. GTX78927

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all TSC2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

201 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized phosphopeptide derived from human Tsc2 around the phosphorylation site of serine 1254 (S-L-Sp-V-P).

Purification

Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
From serum

Conjugation

Unconjugated

RRID

AB_11175369

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

LAM,PPP1R160,TSC2,TSC4,tuberous sclerosis 2,Tuberin,TSC complex subunit 2

Cellular Localization

Cytoplasm,Membrane

Background

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TSC2 (phospho Ser1254) antibody used in IHC (Paraffin sections) (IHC-P). GTX78927

GTX78927 IHC-P Image

IHC-P analysis of human prostate carcinoma tissue using GTX78927 TSC2 (phospho Ser1254) antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399