GeneTex

  • Country / Location Selection

United States (US)

TWEAK antibody

Anti-TWEAK antibody used in Western Blot (WB). GTX16436
Anti-TWEAK antibody used in IHC (Paraffin sections) (IHC-P). GTX16436
Anti-TWEAK antibody used in IHC (Paraffin sections) (IHC-P). GTX16436
Anti-TWEAK antibody used in IHC (Paraffin sections) (IHC-P). GTX16436

Cat. No. GTX16436

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all TWEAK products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 42-123 of human TNFSF12 (NP_003800.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF superfamily member 12 , APO3L , DR3LG , TNLG4A , TWEAK

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]

Database

Research Area

DATA IMAGES

Anti-TWEAK antibody used in Western Blot (WB). GTX16436

GTX16436 WB Image

WB analysis of various sample lysates using GTX16436 TWEAK antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-TWEAK antibody used in IHC (Paraffin sections) (IHC-P). GTX16436

GTX16436 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX16436 TWEAK antibody.
Dilution : 1:100

Anti-TWEAK antibody used in IHC (Paraffin sections) (IHC-P). GTX16436

GTX16436 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX16436 TWEAK antibody.
Dilution : 1:100

Anti-TWEAK antibody used in IHC (Paraffin sections) (IHC-P). GTX16436

GTX16436 IHC-P Image

IHC-P analysis of rat brain tissue using GTX16436 TWEAK antibody.
Dilution : 1:100

REFERENCE

There are currently no references for TWEAK antibody (GTX16436). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for TWEAK antibody (GTX16436). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399