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Tau (phospho Ser396) antibody

Orthogonal
Anti-Tau (phospho Ser396) antibody used in Western Blot (WB). GTX78930

Cat. No. GTX78930

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Mouse
Package
100 μg ($399)
See all Tau products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

79 kDa. ( Note )

Predict Reactivity

Human, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of serine 396 (Y-K-Sp-P-V).

Purification

Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
From serum

Conjugation

Unconjugated

RRID

AB_11167310

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DDPAC,FTDP17,MAPT,MAPTL,MSTD,MTBT1,MTBT2,PPND,PPP1R103,TAU,microtubule associated protein tau,Tau,Neurofibrillary tangles,NFTs

Cellular Localization

Cytoplasm,Cytosol,Cell membrane,Cytoskeleton,Cell projection,Axon

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Tau (phospho Ser396) antibody used in Western Blot (WB). GTX78930

GTX78930 WB Image

Orthogonal

WB analysis of mouse brain tissue lysate using GTX78930 Tau (phospho Ser396) antibody (Lane 3 and 4) and Tau antibody (Lane 1 and 2).

REFERENCE

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REVIEW

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Package List Price ($)
$ 399