APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:3000 |
| 1:100-1:1000 |
Not tested in other applications.
Calculated MW
Positive Control
mouse muscle
Predict Reactivity
Rat, Bovine, Dog, Pig, Rhesus Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Full length human Telethonin Recombinant protein.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_2038107
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
titin-cap , CMD1N , CMH25 , LGMD2G , LGMDR7 , T-cap , TELE , telethonin
Cellular Localization
Cytoplasm , myofibril , sarcomere
Background
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
![Anti-Telethonin antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX109265](/templates/default/js/lightbox/images/loading.gif "Anti-Telethonin antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX109265")
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GTX109265 IHC-P Image
Telethonin antibody [N1C3] detects Telethonin protein at cytoplasm in Huh7 xenograft by immunohistochemical analysis.
Sample: Paraffin-embedded Huh7 xenograft.
Telethonin antibody [N1C3] (GTX109265) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX109265 WB Image
Telethonin antibody detects Telethonin protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with Telethonin antibody (GTX109265) diluted at 1:500.
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REFERENCE
There are currently no references for Telethonin antibody [N1C3] (GTX109265). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Telethonin antibody [N1C3] (GTX109265). Be the first to share your experience with this product.
![Anti-Telethonin antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX109265](/upload/website/prouct_img/small/GTX109265/GTX109265_40023_20160201_IHC-P_w_23060120_416.webp "Anti-Telethonin antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX109265")
![Anti-Telethonin antibody [N1C3] used in Western Blot (WB). GTX109265](/upload/website/prouct_img/small/GTX109265/GTX109265_40023_20150813_WB_M_muscle_w_23060120_586.webp "Anti-Telethonin antibody [N1C3] used in Western Blot (WB). GTX109265")
![Anti-Telethonin antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX109265](/upload/website/prouct_img/normal/GTX109265/GTX109265_40023_20160201_IHC-P_w_23060120_416.webp "Anti-Telethonin antibody [N1C3] used in IHC (Paraffin sections) (IHC-P). GTX109265")
![Anti-Telethonin antibody [N1C3] used in Western Blot (WB). GTX109265](/upload/website/prouct_img/normal/GTX109265/GTX109265_40023_20150813_WB_M_muscle_w_23060120_586.webp "Anti-Telethonin antibody [N1C3] used in Western Blot (WB). GTX109265")