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Tyrosine Hydroxylase antibody

Anti-Tyrosine Hydroxylase antibody used in Immunohistochemistry (IHC). GTX85470
Anti-Tyrosine Hydroxylase antibody used in IHC (Paraffin sections) (IHC-P). GTX85470
Anti-Tyrosine Hydroxylase antibody used in IHC (Paraffin sections) (IHC-P). GTX85470
Anti-Tyrosine Hydroxylase antibody used in Immunohistochemistry (IHC). GTX85470
Anti-Tyrosine Hydroxylase antibody used in IHC (Paraffin sections) (IHC-P). GTX85470
Anti-Tyrosine Hydroxylase antibody used in IHC (Paraffin sections) (IHC-P). GTX85470
Anti-Tyrosine Hydroxylase antibody used in Immunohistochemistry (IHC). GTX85470
Anti-Tyrosine Hydroxylase antibody used in IHC (Paraffin sections) (IHC-P). GTX85470

Cat. No. GTX85470

Host

Chicken

Clonality

Polyclonal

Isotype

IgY

Application

WB, ICC/IF, IHC-P, IHC

Reactivity

Human, Mouse, Rat
Package
50 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000-1:2000
ICC/IF Assay dependent
IHC-P Assay dependent
IHC 1:1000-1:2000
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Chickens were immunized with two synthetic peptide / keyhole limpet hemocyanin (KLH) conjugates. These synthetic peptides corresponded to different regions of the Tyrosine Hydroxylase gene product, but were shared between the human (P07101, NCBI) and mouse (P24529, NCBI) sequences.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tyrosine hydroxylase , DYT14 , DYT5b , TYH

Background

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Tyrosine Hydroxylase antibody used in Immunohistochemistry (IHC). GTX85470

GTX85470 IHC Image

IHC analysis of unfixed, thick vibratome sections of adult rat brain Rostral Ventral Lateral Medulla (RVLM) using GTX85470 Tyrosine Hydroxylase antibody.
Dilution : 1:1000

Anti-Tyrosine Hydroxylase antibody used in IHC (Paraffin sections) (IHC-P). GTX85470

GTX85470 IHC-P Image

IHC-P analysis of paraformaldehyde-fixed (4%) substantia nigra pars compacta of an adult mouse brain using GTX85470 Tyrosine Hydroxylase antibody. This mouse was engineered to have GFP expressed under control of the actin promoter, which explains the low-level green autofluorescence. Note the high number of dopaminergic neuron cell bodies in this brain region.

Anti-Tyrosine Hydroxylase antibody used in IHC (Paraffin sections) (IHC-P). GTX85470

GTX85470 IHC-P Image

IHC-P analysis of paraformaldehyde-fixed (4%) substantia nigra pars compacta of an adult mouse brain using GTX85470 Tyrosine Hydroxylase antibody. This mouse was engineered to have GFP expressed under control of the actin promoter, which explains the low-level green autofluorescence. Note the high number of dopaminergic neuron cell bodies in this brain region.

Anti-Tyrosine Hydroxylase antibody used in Immunohistochemistry (IHC). GTX85470

GTX85470 IHC Image

IHC analysis of unfixed, thick vibratome sections of adult rat brain Rostral Ventral Lateral Medulla (RVLM) using GTX85470 Tyrosine Hydroxylase antibody.
Dilution : 1:1000

Anti-Tyrosine Hydroxylase antibody used in IHC (Paraffin sections) (IHC-P). GTX85470

GTX85470 IHC-P Image

IHC-P analysis of paraformaldehyde-fixed (4%) caudate nucleus of an adult mouse brain using GTX85470 Tyrosine Hydroxylase antibody.This mouse was engineered to have GFP expressed under control of the actin promoter, which explains the low-level green autofluorescence. Note the high number of dopaminergic fibers in this brain region.

Anti-Tyrosine Hydroxylase antibody used in IHC (Paraffin sections) (IHC-P). GTX85470

GTX85470 IHC-P Image

IHC-P analysis of paraformaldehyde-fixed (4%) caudate nucleus of an adult mouse brain using GTX85470 Tyrosine Hydroxylase antibody.This mouse was engineered to have GFP expressed under control of the actin promoter, which explains the low-level green autofluorescence. Note the high number of dopaminergic fibers in this brain region.

Anti-Tyrosine Hydroxylase antibody used in Immunohistochemistry (IHC). GTX85470

GTX85470 IHC Image

IHC analysis of unfixed, thick vibratome sections of adult rat brain Rostral Ventral Lateral Medulla (RVLM) using GTX85470 Tyrosine Hydroxylase antibody.
Dilution : 1:1000

Anti-Tyrosine Hydroxylase antibody used in IHC (Paraffin sections) (IHC-P). GTX85470

GTX85470 IHC-P Image

IHC-P analysis of paraformaldehyde-fixed (4%) caudate nucleus of an adult mouse brain using GTX85470 Tyrosine Hydroxylase antibody.This mouse was engineered to have GFP expressed under control of the actin promoter, which explains the low-level green autofluorescence. Note the high number of dopaminergic fibers in this brain region.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399