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UVRAG antibody

Anti-UVRAG antibody used in Western Blot (WB). GTX65976
Anti-UVRAG antibody used in IHC (Paraffin sections) (IHC-P). GTX65976
Anti-UVRAG antibody used in IHC (Paraffin sections) (IHC-P). GTX65976
Anti-UVRAG antibody used in IHC (Paraffin sections) (IHC-P). GTX65976

Cat. No. GTX65976

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all UVRAG products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

78 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 501-699 of human UVRAG (NP_003360.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

UV radiation resistance associated , DHTX , VPS38 , p63

Cellular Localization

Lysosome,Endoplasmic reticulum

Background

This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-UVRAG antibody used in Western Blot (WB). GTX65976

GTX65976 WB Image

WB analysis of various sample lysates using GTX65976 UVRAG antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-UVRAG antibody used in IHC (Paraffin sections) (IHC-P). GTX65976

GTX65976 IHC-P Image

IHC-P analysis of rat lung tissue using GTX65976 UVRAG antibody.
Dilution : 1:100

Anti-UVRAG antibody used in IHC (Paraffin sections) (IHC-P). GTX65976

GTX65976 IHC-P Image

IHC-P analysis of human liver damage tissue using GTX65976 UVRAG antibody.
Dilution : 1:100

Anti-UVRAG antibody used in IHC (Paraffin sections) (IHC-P). GTX65976

GTX65976 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX65976 UVRAG antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399