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VAP1 antibody [174-5]

Cat. No. GTX54473

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 174-5

Isotype

 IgG1

Application

 ICC/IF, IHC-Fr, FACS, Neutralizing/Inhibition

Reactivity

 Human
Package
50 μg ($399)
See all VAP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

IHC-Fr
Tissue sections were fixed in acetone before staining with 174-5.

Neutralizing/Inhibition
Antibody 174-5 inhibits lymphocyte infiltration in liver allograft rejection. The antibody was administered intravenously at a concentration of 2 mg/kg.
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Product Note

The monoclonal antibody 174-5 has been shown to inhibit lymphocyte infiltration in rat liver allograft rejection.

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS, 0.1% BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

100 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified vessels from human peripheral lymph nodes (ref 1)

Purification

Purified IgG1

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AOC3,HPAO,SSAO,VAP1,amine oxidase, copper containing 3,amine oxidase copper containing 3

Cellular Localization

Cell membrane

Background

This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399