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VLDL Receptor antibody [1H5]

Cat. No. GTX79551

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1H5

Isotype

 IgG1

Application

 ELISA, Neutralizing/Inhibition

Reactivity

 Human
Package
500 μg ($399)
See all VLDL Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ELISA Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

96 kDa. ( Note )

Product Note

Recognises the C-terminus of VLDL receptor ligand binding domain (191-355)

PROPERTIES

Form

Liquid

Buffer

0.05M Sodium Phosphate, 0.1M NaCl, 1mM EDTA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of soluble VLDL receptor containing ligand binding repeats 1-8 (sVLDLr1-8).

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

RRID

AB_11163500

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CAMRQ1,CARMQ1,CHRMQ1,VLDLR,VLDLRCH,very low density lipoprotein receptor,VLDL receptor

Cellular Localization

Membrane,Clathrin-coated pit

Background

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009]

Database

Research Area

REFERENCE

Application Reference

M Martikainen et al. Research Square 2023; VLDLR mediates alphavirus neuroinvasion through the blood-cerebrospinal fluid barrier
Application : Neutralizing/Inhibition
Reactivity : Human
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REVIEW

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Package List Price ($)
$ 399